- Recruiting
- Health services research
- Interventional
- Behavioral
- Henry Ford Health System
- 18 Years -
Study Purpose
This is a pilot study to improve rates of germline genetic testing for black patients with aggressive prostate cancer as recommended by the updated guidelines by the National Cancer Comprehensive Network (NCCN) in 2018. In this study, consented patients will undergo a low-risk intervention of an educational session with a trained staff member on germline testing in prostate cancer and, if agreeable, subsequent germline cancer genetic testing via a commercial lab test.
Intervention
Behavioral : Educational video
Eligibility Requirements
Men, age greater than or equal to 18 years of age.
Men who racially identify as black or multiracial including black
Diagnosis of prostate cancer of any histology.
Must meet NCCN guidelines for germline testing
1. Men with very low, low or intermediate risk prostate per NCCN guidelines with a positive family history or intraductal histology. Family history here is considered significant if the patient has:
* a first degree relative with prostate cancer or more than one first/second degree relative with prostate cancer, or
* ≥3 cancers on same side of family, especially diagnoses ≤50 years of age: bile duct, breast, colorectal, endometrial, gastric, kidney, melanoma, ovarian, pancreatic, prostate (but not clinically localized Grade Group 1), small bowel, or urothelial cancer 2. Men with high-risk, very-high risk (per NCCN definitions of risk groups), lymph node positive, or metastatic prostate cancer independent of family history of histology.
Have had prior germline testing.
Have somatic genetic testing that is positive for a possible germline variant.
Recruiting status
Recruiting
Estimated enrollment
50
Study start date
Jan 01, 2025
Study end date
Jun 30, 2026
Last updated
Mar 23, 2025
Primary purpose
Health services research
Design
Interventional
Intervention
Behavioral
Study phase
NA
Allocation
Na
Sponsor:
Henry Ford Health System
Collaborator:
N/A
Investigator:
N/A
Publications
N/A
Websites
N/A
NCT05958082
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